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Had taken Micardis. Worked very well. Then Dr. said I could go on lisinopril. It would be much cheaper. Had a terrible cough. Then he switched me to losartan. Been on this a week and cough is much worse. I did not have a problem paying for Micardis. I'm going back.
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Cozaar seems to be helping, although I'm on the smallest dosage. My blood pressure is almost back to normal.

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One patient discontinued taking losartan potassium and hydrochlorothiazide tablets due to a minor increase in serum creatinine.

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Losartan, an orally active angiotensin (AT1) receptor antagonist: a review of its efficacy and safety in essential hypertension.

Losartan which has the active ingredient Losartan Potassium is also sold as Losacar-A, Hyzaar, Cozaar, Cosart and under various other brand names.

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Hg) was significantly greater than reductions with losartan and valsartan (6.

Angiotensin II receptor blockers versus angiotensin-converting enzyme inhibitors in patients with stable coronary artery disease: Prevalence, correlates, and prognostic impact (from the CORONOR study).

Advise patient to monitor and record BP and pulse at home and to inform health care provider if abnormal measurements are noted.

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Read the Patient Information that comes with Losartan Potassium and Hydrochlorothiazide Tablets before you start taking it and each time you get a refill.

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In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with angiotensin II receptor antagonists (including Losartan) may result in deterioration of renal function, including possible acute renal failure.

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Mean peak concentrations of Losartan and its active metabolite are reached in 1 hour and in 3 to 4 hours, respectively.

It is the fraction of the drug absorbed through non-intravenous administration compared with the corresponding intravenous administration of the same drug.

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There was no significant difference between the losartan group and the placebo group in the composite secondary end point of morbidity and mortality from cardiovascular causes.

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In patients with cirrhosis, however, significantly increased plasma concentrations of parent drug and active metabolite have been reported.

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Goldberg AI, Dunlay MC, Sweet CS "Safety and tolerability of losartan potassium, and angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension.

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Long-term trials are needed to evaluate cardiovascular end points, efficacy after myocardial infarction and dose response.

Alert your doctor if you believe you are taking any medications listed under Major Interactions as these result in potentially life threatening side effects.

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